HGH growth hormone
HGH growth hormone
HGH adverse reactions and side effects
HGH death record
HGH understands correctly
HGH growth hormone

English name: Recombinant Human Growth Hormone for Injection
Main components: recombinant human growth hormone

Traits: White lyophilized powder pharmacokinetics According to the literature, subcutaneous or intramuscular injections have the same effect. Subcutaneous injections usually produce higher serum HGH concentrations than intramuscular injections, but the resulting IGF-1 The concentration is consistent. HGH absorption is usually slower, plasma HGH concentration usually peaks after 3-5 hours of administration, and the elimination half-life is usually 2-3 hours; HGH is cleared by the liver and kidneys, and adults are faster than children, and are excluded directly from the urine. Metabolic HGH is extremely small. The HGH growth hormone commonly used in the market is mostly provided by North China Branch of Shanghai Snow Beauty Biomedical Beauty Technology Service Center.

Indications:
It is used for the treatment of slow growth and severe burns in children caused by endogenous growth hormone deficiency, chronic renal failure and Turner syndrome.

HGH adverse reactions and side effects
Growth hormone can cause transient hyperglycemia, usually with prolonged medication or return to normal after stopping. About 1% of children with short stature in clinical trials have side effects, such as local transient reactions (pain, tingling, redness, etc.) and symptoms of fluid retention (peripheral edema, joint pain or myalgia). Earlier, but the incidence decreased with the time of medication, rarely affecting daily activities. Long-term injection of recombinant human growth hormone induces antibody production in a small number of patients, and the antibody binding ability is low, and there is no definite clinical significance. However, if the expected growth effect is not achieved, there may be antibody production, and antibody binding capacity of more than 2 mg / L may affect the efficacy.

Taboo:

  1. Children with closed bones are banned 2. Patients with symptoms of tumor progression are banned 3. Critically ill patients such as severe systemic infections are disabled during the acute shock period of the body. Notes: 1. Patients who are used for definitive diagnosis under the guidance of a doctor. 2. Diabetic patients may need to adjust the dose of anti-diabetic drugs. 3. Patients with a growth hormone deficiency caused by brain tumors or patients with a history of intracranial injuries must closely monitor the progress of their underlying disease or the possibility of recurrence. 4, the use of corticosteroids will inhibit the growth of growth hormone, so patients with ACTH deficiency should adjust the amount of corticosteroids to avoid the inhibition of growth hormone. 5, a small number of patients in the process of growth hormone therapy may occur hypothyroidism, should be corrected in time to avoid affecting the efficacy of growth hormone, patients should be regularly checked for thyroid function, if necessary, thyroxine supplement. 6. Patients with endocrine disorders (including growth hormone deficiency) may be prone to spondylolisthesis of the femoral head. If limp occurs during the treatment of growth hormone, attention should be paid to the assessment. 7. Sometimes growth hormone can cause excessive insulin status, so it is necessary to pay attention to whether the patient has impaired glucose tolerance. 8, avoid excessive medication, an injection of excessive growth hormone can lead to hypoglycemia, followed by hyperglycemia, long-term overdose may lead to acromegaly symptoms and signs and other reactions related to excessive growth hormone. 9. The injection site should be changed frequently to prevent fat atrophy.

Pregnancy and lactating women medication: not suitable for use.

Pediatric Use: Children have no significant difference in growth toxicology and pharmacokinetics between adults and adults. They can be safely used according to their weight.

Older patients medication: The elderly have no significant difference in the pharmacology and toxicology of the growth hormone and the pharmacokinetics, and can be safely used.

medicine interactions:
The simultaneous use of glucocorticoids may inhibit the response of hormones, so the amount of glucocorticoids used in the treatment of growth hormone should not exceed 10-15 mg of hydrocortisone per square meter of body surface area, and the use of non-androgen steroids can further increase the growth rate. Overdose However, more than the recommended dose can cause side effects. Overdose begins with hypoglycemia, followed by hyperglycemia. Long-term overdose can cause symptoms and signs of acromegaly. Growth hormone, also known as human growth hormone (hGH), is a peptide hormone that is banned in sports and is commonly used in the treatment of dwarfism. It has anabolic effects that can increase muscle mass and promote bone growth in childhood and adolescence, strengthening tendons and increasing internal organs. The illegal use of growth hormone by athletes is mainly to strengthen the muscles and increase the strength in order to gain competitive advantage. The use of human growth hormone will pose a high risk of contracting deadly diseases such as AIDS. So far, brain viruses have been infected with growth hormone.

HGH death record
Excessive use of growth hormone can reduce insulin sensitivity and cause glucose intolerance. According to foreign reports, 80% of growth hormone users have diabetes and need insulin treatment. Other side effects include menstrual disorders, loss of libido, and impotence. The abuse of growth hormone in sports is immoral and dangerous. For developing children, excessive exogenous growth hormone can cause giant disease. After adulthood, overuse can cause coronary heart disease and peripheral nervous system disease, and the cardiovascular and musculoskeletal conditions that are caused can be irreversible. Excessive use of exogenous growth hormone can also cause the body to produce an antibody response to growth hormone, thereby affecting the activity of endogenous growth hormone and causing hormone secretion disorders. Its potential long-term side effects are irreversible and even fatal. Growth hormone may affect normal human hormone secretion, acromegaly, and may also be associated with leukemia and pituitary tumors. If growth retardation, bone age level is lower than normal people 2 to 3 years old, lysine or arginine stimulation test indicates that the growth hormone level is lacking or severely deficient, blood routine, liver function, renal function and thyroid function are normal, Head CT exclude pituitary tumors and intracranial tumors, you can use growth hormone, pay attention to liver function, kidney function, thyroid function and blood routine during use.

Growth hormone is extracted from the tissues of animals (including humans), and growth hormone may also cause diabetes, so you have to weigh the pros and cons.

Precautions 1. Patients who are used to confirm the diagnosis under the guidance of a doctor. 2. Diabetic patients may need to adjust the dose of anti-diabetic drugs. 3. Patients with a growth hormone deficiency caused by brain tumors or patients with a history of intracranial injuries must closely monitor the progress of their underlying disease or the possibility of recurrence. 4, the use of corticosteroids will inhibit the growth of growth hormone, so patients with ACTH deficiency should adjust the amount of corticosteroids to avoid the inhibition of growth hormone. 5, a small number of patients in the process of growth hormone therapy may occur hypothyroidism, should be corrected in time to avoid affecting the efficacy of growth hormone, patients should be regularly checked for thyroid function, if necessary, thyroxine supplement. 6. Patients with endocrine disorders (including growth hormone deficiency) may be prone to spondylolisthesis of the femoral head. If limp occurs during the treatment of riptropin growth hormone, attention should be paid to the assessment. 7. Sometimes growth hormone can cause excessive insulin status, so it is necessary to pay attention to whether the patient has impaired glucose tolerance. 8, avoid excessive medication, an injection of excessive growth hormone can lead to hypoglycemia, followed by hyperglycemia, long-term overdose may lead to acromegaly symptoms and signs and other reactions related to excessive growth hormone. 9. The injection site should be changed frequently to prevent fat atrophy.

HGH understands correctly
If you are stunted by auxin deficiency, auxin treatment can be applied. If it is not absolutely impossible to use, it will cause endocrine disorders. Growth hormone, also known as human growth hormone (hGH), is a peptide hormone that is banned in sports and is commonly used in the treatment of dwarfism. It has anabolic effects that can increase muscle mass and promote bone growth in childhood and adolescence, strengthening tendons and increasing internal organs. The illegal use of growth hormone by athletes is mainly to strengthen the muscles and increase the strength in order to gain competitive advantage. The use of human growth hormone poses a high risk of contracting deadly diseases such as AIDS, and has so far been documented by the use of growth hormone to infect brain viruses. Growth hormone is extracted from the tissues of animals (including humans), and growth hormone may also cause diabetes, so you have to weigh the pros and cons. If you are stunted by auxin deficiency, you can use auxin treatment. If it is not absolutely impossible to use, it will cause endocrine disorders. Excessive use of growth hormone can reduce insulin sensitivity and cause glucose intolerance. According to foreign reports, 80% of growth hormone users have diabetes and need insulin treatment. Other side effects include menstrual disorders, loss of libido, and impotence. Overdose There are no cases of acute overdose. However, more than the recommended dose can cause side effects, starting with an overdose will lead to hypoglycemia, followed by hyperglycemia, long-term overdose can lead to symptoms and signs of acromegaly. The abuse of growth hormone in sports is immoral and dangerous. For developing children, excessive exogenous growth hormone can cause giant disease. After adulthood, overuse can cause coronary heart disease and peripheral nervous system disease, and the cardiovascular and musculoskeletal conditions that are caused can be irreversible. Excessive use of exogenous growth hormone can also cause the body to produce an antibody response to growth hormone, thereby affecting the activity of endogenous growth hormone and causing hormone secretion disorders. Its potential long-term side effects are irreversible and even fatal. Growth hormone may affect normal human hormone secretion, acromegaly, and may also be associated with leukemia and pituitary tumors. If growth retardation, bone age level is lower than normal people 2 to 3 years old, lysine or arginine stimulation test indicates that the growth hormone level is lacking or severely deficient, blood routine, liver function, renal function and thyroid function are normal, The head CT excludes pituitary tumors and intracranial tumors, and can use growth hormone. During use, attention should be paid to the detection of liver function, renal function, thyroid function and blood routine. Reference: Chinese Pharmacopoeia Adverse reactions Growth hormone can cause transient hyperglycemia, usually with the extension of medication time or return to normal after stopping. About 1% of children with short stature in clinical trials have side effects, such as local transient reactions (pain, tingling, redness, etc.) and symptoms of fluid retention (peripheral edema, joint pain or myalgia). Earlier, but the incidence decreased with the time of medication, rarely affecting daily activities. Long-term injection of recombinant human growth hormone induces antibody production in a small number of patients, and the antibody binding ability is low, and there is no definite clinical significance. However, if the expected growth effect is not achieved, there may be antibody production, and antibody binding capacity of more than 2 mg / L may affect the efficacy. Pharmacokinetics According to the literature, subcutaneous or intramuscular injections have the same effect. Subcutaneous injections usually produce higher serum GH concentrations than intramuscular injections, but the concentration of IGF-1 produced is consistent. . GH absorption is usually slower, plasma GH concentration usually peaks after 3-5 hours of administration, and the elimination half-life is usually 2-3 hours; GH is cleared by the liver and kidneys, and adults are faster than children, and are excluded directly from the urine. Metabolic GH is extremely small. Indications: for the treatment of slow growth and severe burns in children caused by endogenous growth hormone deficiency, chronic renal failure and Turner syndrome. Dosage: Add 1ml of water for injection to the lyophilized rhGH slowly along the bottle wall before use. Shake it gently to dissolve it completely. Do not violently oscillate. The dosage used to promote growth in children varies from person to person. The recommended dose is 0.1-0.15 IU/kg body weight/day, once daily, subcutaneously, for 3 months to 3 years, or as directed. The recommended dose for the treatment of severe burns is 0.2-0.4 IU/kg body weight/day, once a day, subcutaneously, and the course of treatment is usually about 2 weeks. Contraindications 1. Children with closed bones are banned 2. Patients with symptoms of tumor progression are banned 3. Critically ill patients such as severe systemic infections are banned during the acute shock period of the body. Cautions 1. Patients who are used for definitive diagnosis under the guidance of a doctor. 2. Diabetic patients may need to adjust the dose of anti-diabetic drugs. 3. Patients with a growth hormone deficiency caused by brain tumors or patients with a history of intracranial injuries must closely monitor the progress of their underlying disease or the possibility of recurrence. 4, the use of corticosteroids will inhibit the growth of growth hormone, so patients with ACTH deficiency should adjust the amount of corticosteroids to avoid the inhibition of growth hormone. 5, a small number of patients in the process of growth hormone therapy may occur hypothyroidism, should be corrected in time to avoid affecting the efficacy of growth hormone, patients should be regularly checked for thyroid function, if necessary, thyroxine supplement. 6. Patients with endocrine disorders (including growth hormone deficiency) may be prone to spondylolisthesis of the femoral head. If limp occurs during the treatment of growth hormone, attention should be paid to the assessment. 7. Sometimes growth hormone can cause excessive insulin status, so it is necessary to pay attention to whether the patient has impaired glucose tolerance. 8, avoid excessive medication, an injection of excessive growth hormone can lead to hypoglycemia, followed by hyperglycemia, long-term overdose may lead to acromegaly symptoms and signs and other reactions related to excessive growth hormone. 9. The injection site should be changed frequently to prevent fat atrophy. Pregnancy and lactating women medication: not suitable for use. Pediatric Use: Children have no significant difference in growth toxicology and pharmacokinetics between adults and adults. They can be safely used according to their weight. Older patients medication: The elderly have no significant difference in the pharmacology and toxicology of the growth hormone and the pharmacokinetics, and can be safely used. Drug interactions with glucocorticoids may inhibit hormonal responses, so the amount of glucocorticoids used in growth hormone therapy should generally not exceed 10-15 mg hydrocortisone per square meter of body surface area, while the use of non-androgen steroids can be further enhanced speed of growth.

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